Singapore, May 12 -- BioIVT, a leading provider of research models and services for drug and diagnostic development, on 11 May 2020 announced that it is adding high-purity Kupffer cells to its portfolio of human primary hepatic cells to support liver disease drug discovery and development and help predict adverse drug reactions.

Kupffer cells perform a scavenger role in the liver, removing small particles, senescent cells and cell debris. They also play an important role in the immune response to liver pathogens. Dysregulation of the Kupffer cell response contributes to chronic inflammation, leading to liver diseases such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and liver fibrosis. NASH is a type ...