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Singapore Clinical Trial: A Phase 1, Randomized, Placebo-Controlled, Single- and Multiple-Ascending Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4247147 in Participants with Obesity or Overweight who are Otherwise Healthy

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Randomized, Placebo-Controlled, Single- and Multiple-Ascending Dose Escalation Study to ... Read More


Singapore Clinical Trial: A Phase II, Open-label Platform Study of Osimertinib in Combination with Anti-cancer Agents in Participants With EGFR-mutated Metastatic Non-small Cell Lung Cancer Whose Disease Has Progressed on Prior Osimertinib and Chemotherapy Combination Treatment (GROVE)

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A Phase II, Open-label Platform Study of Osimertinib in Combination with Anti-cancer Agents in Part... Read More


Singapore Clinical Trial: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial To Evaluate The Efficacy And Safety Of Enicepatide In Participants With Overweight Or Obesity And Heart Failure With Reduced Ejection Fraction

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial To Evaluate The Efficacy And Safet... Read More


Singapore Clinical Trial: A two-part, First-In-Human, phase I, open-label, ascending dose study to assess safety and tolerability of DKB903 in participants with Rheumatoid Arthritis (RA) and participants with Systemic Lupus Erythematosus (SLE).

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A two-part, First-In-Human, phase I, open-label, ascending dose study to assess safety and tolerabi... Read More


Singapore Clinical Trial: A Phase 2, Randomized, Open-Label Dose Optimization and Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Tersolisib (LY4064809) Combined with a CDK4/6 Inhibitor and Endocrine Therapy in Adults with HR+, HER2- Advanced Breast Cancer with a PIK3CA Mutation Who Received No Prior Treatment for Advanced Breast Cancer (PIKALO-2)

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A Phase 2, Randomized, Open-Label Dose Optimization and Phase 3, Randomized, Double-Blind, Placebo-... Read More


Singapore Clinical Trial: A Phase 1 Open-Label Study to Determine the Effect of Injection Site on the Relative Bioavailability of a Single Subcutaneous Dose of LY3841136 and to Evaluate the Pharmacokinetics of a Single Intravenous Dose of LY3841136 in Healthy Participants.

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 Open-Label Study to Determine the Effect of Injection Site on the Relative Bioavailabilit... Read More


Singapore Clinical Trial: Efficacy of Yang Shen Dan in Mild to Moderate Alzheimer’s Disease: Randomised controlled study

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'Efficacy of Yang Shen Dan in Mild to Moderate Alzheimer’s Disease: Randomised controlled study'. Th... Read More


Singapore Clinical Trial: A First-in-Human, Open-Label, Multi-Center Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ALK201 for Injection in Adult Participants with Advanced Solid Tumors

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A First-in-Human, Open-Label, Multi-Center Phase I/II Clinical Study to Evaluate the Safety, Tolera... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine (MK-5884) Versus Placebo for the Prevention of COPD Exacerbations in Adults with a History of Moderate or Severe Exacerbations While Receiving Standard of Care (ENHANCE-3)

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety o... Read More


Singapore Clinical Trial: An open-label, roll-over study evaluating the long-term safety and efficacy of an oral dose of verducatib q.d. in patients with bronchiectasis (AIRTIVITY®-ON)

Singapore, Nov. 6 -- The Health Sciences Authority received information related to the study titled 'An open-label, roll-over study evaluating the long-term safety and efficacy of an oral dose of verd... Read More