U.S., July 15 -- ClinicalTrials.gov registry received information related to the study (NCT07063251) titled 'An Clinical Study Evaluating the Safety, Tolerability, and efficAcy of HG005 in StaRgardT Disease' on July 03.
Brief Summary: Stargardt disease type 1 (STGD1) is a rare genetic eye condition that causes progressive vision loss, often beginning in childhood or adolescence. It is the most common form of inherited macular degeneration and can lead to legal blindness. STGD1 is caused by mutations in the ABCA4 gene, which normally helps clear waste from the photoreceptor cells in the retina. When ABCA4 gene doesn't function properly, toxic substances like A2E accumulate and damage the retinal pigment epithelium (RPE), leading to vision l...