India, Feb. 3 -- Constant travel to glamorous places has a way of catching up with your skin, your sleep, and your sense of equilibrium. Just ask Kelly Wearstler. As one of the most influential hotel designers today, the Los Angeles-based Wearstler spends much of her life skipping time zones for hotel openings, project check-ins, and scouting trips.

Since first reshaping Los Angele's 's boutique-hotel scene with the Avalon Hotel Beverly Hills in 1999 and the Viceroy Santa Monica shortly after, Wearstler's portfolio has expanded alongside her global footprint. Today, projects like L'Apogee Courchevel, Four Resort Seasons Anguilla (formerly the Viceroy), and her ongoing collaboration with Proper Hotels routinely pull her from California to...