New York, June 26 -- Bacteria causing typhoid fever are becoming increasingly resistant to some of the most important antibiotics for human health, according to a study published in The Lancet Microbe journal.

The largest genome analysis of Salmonella enterica serovar Typhi (S. Typhi) also reveals that resistant strains - almost all originating in South Asia - have spread to other countries nearly 200 times since 1990.

Typhoid fever is a global public health concern, causing 11 million infections and more than 100,000 deaths per year. While it is most prevalent in South Asia - which accounts for 70 per cent of the global disease burden - it also has significant impacts in sub-Saharan Africa, Southeast Asia, and Oceania, highlighting the...