US FDA Approves First CAR T-Cell Therapy for Marginal Zone Lymphoma In the US
United States, Dec. 4 -- The U.S. Food and Drug Administration approved a new indication for Breyanzi (Lisocabtagene maraleucel) as the first Chimeric Antigen Receptor (CAR) T-cell therapy in the U.S. for treatment of adults with marginal zone lymphoma (MZL) who have failed treatment with or relapsed after two or more prior lines of therapy. Breyanzi is a chimeric antigen receptor CAR T-cell therapy that genetically engineers a patient's own T-cells to target and kill cancer cells. Marginal zone lymphoma is a rare slow-growing cancer of the lymphatic system. It presents about 7% of all B-cell non-Hodgkin lymphoma, with approximately 7,460 new cases occurring every year in the U.S. population. Patients with MZL who failed treatment or relaps...
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