Switzerland, March 2 -- Project Id: 105571
Description: Optical imaging in cancer metabolic reprogramming studies
Recent studies show that cancer tissues possess several important metabolic features, including the differential utilisation of essential metabolites. This phenomenon, termed as metabolic reprogramming, is a prerequisite for malignant transformation and tumor progression. A better understanding of metabolic reprogramming in specific tumors can lead to more effective cancer treatments. The goal of the EU-funded METABOLIGHT project is to address the unmet need for nutrient uptake imaging tools by developing a novel platform based on a combination of 'click' chemistry reactions and noninvasive, ultra-sensitive bioluminescent imag...