Japan, Dec. 17 -- Kirin Holdings Company, Limited and Fujitsu Limited have jointly conducted research on food functionality simulation with the goal of creating new functionalities in food. This research utilized QSP (Quantitative Systems Pharmacology) models, one of the AI-driven digital transformation (DX) technologies for drug discovery, combined with real-world experimental validation. As a result, the study has, for the first time worldwide, identified a previously unknown mechanism within the gut-brain axis associated with citicoline, a compound known for its role in supporting cognitive health. This finding was obtained by combining virtual subject simulations based on advanced QSP technologies developed by Fujitsu in collaboration w...