New Delhi, March 11 -- Prince Frederik, the youngest son of Prince Robert of Luxembourg, has passed away at the age of 22 due to a rare genetic disorder. His father, alongside Princess Julie of Nassau, announced the heartbreaking news on the POLG Foundation website-a nonprofit charity founded by Frederik in 2022. Born with POLG mitochondrial disease and diagnosed at 14, Frederik's struggle with the disorder was a constant part of his short yet impactful life.

On February 28, during Rare Disease Day, Frederik gathered his loved ones for one final conversation. He spoke to his family, sharing "some kind, some wise, (and) some instructive" farewells, and even left them with a long-standing family joke.

"Even in his last moments, his humor,...