New Delhi, Nov. 11 -- Drug regulators in various states have issued warning notices to manufacturers to close operations for not complying with good manufacturing practices, three officials familiar with the matter said.

Delhi, Himachal Pradesh and Uttarakhand are among the states that have already initiated action, the people said. The development follows the Drugs Controller General of India (DCGI) directing regulators in all states and Union territories to conduct urgent inspections and take action.

"The DCGI has issued strict and final directions to all state authorities because every pharmaceutical company must ensure full compliance with the updated GMP. Failure to meet the upgrade deadline means they have to shut down operations ...