India, Sept. 14 -- The Houston Texans opened the season with uncertainty after running back Joe Mixon was placed on the Non-Football Injury (NFI) list. The move ensures the veteran will miss at least the first four games of the 2025-26 campaign.

Mixon, who joined the Texans from the Bengals, was expected to be a key piece for quarterback C.J. Stroud. Without him, Houston's offense showed thin depth in its loss to the Rams.

According to ProFootballNetwork.com, injury analyst Jeff Mueller reported that he received troubling information about Mixon from multiple sources. Head coach DeMeco Ryans admitted the team has to move forward with the players on the roster.

"We're rolling with the guys that are here. That's the main thing," Ryans sa...