International Clinical Trial: The effectiveness of Metformin for reducing weight gain experienced by people with severe mental health problems in South Asia

Geneva, May 16 -- International Clinical Trials Registry received information related to the study (ISRCTN23496771) titled 'The effectiveness of Metformin for reducing weight gain experienced by people with severe mental health problems in South Asia' on May 12 2025.

Study Type: Interventional

Study Design: Two-armed parallel individually randomized triple-blind control trial (Treatment, Safety, Efficacy)

Primary Sponsor: University of York

Condition: Attenuation of antipsychotic induced weight gain in people with severe mental illness. Mental and Behavioural Disorders

Intervention: Intervention: Film coated tablets of metformin XR, starting at 500 mg daily and titrating up to 2000 mg daily over a 6-week period, orally for a total...