Geneva, Oct. 21 -- International Clinical Trials Registry received information related to the study (JPRN-UMIN000059172) titled 'Exploratory Single-Arm Interventional Study of Scheduled, Continued Loperamide for Abemaciclib-Induced Diarrhea: Evaluation of Diarrhea and Impact on Daily Activities' on Sept. 24.

Study Type: Interventional

Study Design: Single arm Non-randomized

Primary Sponsor: Yokohama Asahi Chuo General Hospital

Condition: Hormone Receptor-Positive, HER2-Negative Breast Cancer (Advanced/Recurrent or Adjuvant Setting)

Intervention: When loose stools (Bristol Stool Scale type 6 or 7) occur after initiation of abemaciclib, loperamide 1 mg twice daily will be administered and continued with the same dosing schedule unti...