International Clinical Trial: Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)

Geneva, Oct. 21 -- International Clinical Trials Registry received information related to the study (NCT07210112) titled 'Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)' on Sept. 29.

Study Type: Interventional

Study Design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor).

Primary Sponsor: Centre Hospitalier St Anne

Condition: Depression - Major Depressive Disorder Treatment-resistant Depression (TRD)

Intervention: Drug: Psilocybin 25 mg per os Drug: Trazodone 5mg Drug: Trazodone 30 mg Drug: Placebo of psilocybin...