U.S., Dec. 13 -- ClinicalTrials.gov registry received information related to the study (NCT07280195) titled 'ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty' on Nov. 20.

Brief Summary: The purpose of this study is to determine if local intra-operative application of ZYNRELEF (topical medication) during shoulder replacement surgery improves pain control (as defined by opioid consumption after surgery) compared to the use of an interscalene block with catheter. This is a randomized clinical trial without blinding. Subjects will complete patient reported outcomes before and after surgery. Subjects will track their narcotic use, pain scores and pain satisfaction after surgery.

Study Start Date: Dec., 2025 ...