U.S., Sept. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07190287) titled 'Wearable Neural Interfacing System for REM Sleep Restoration and Enhancement' on July 31.
Brief Summary: This study evaluates a wearable system (NEUSleeP) that combines overnight EEG recording with transcranial focused ultrasound (tFUS) targeted to deep brain structures involved in REM sleep regulation (e.g., subthalamic nucleus). The primary objective is to assess safety and estimate effects on REM sleep quantity and architecture; secondary objectives include changes in stress-related measures.
Healthy adults aged 18-50, with or without subclinical sleep or stress complaints, will complete two consecutive overnight recordings: Ni...