U.S., Feb. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07380477) titled 'VentricuLostomy AssoCiaTed InfeCtions (LACTIC): Focus on CSF Lactate and Sampling Site' on Jan. 06.
Brief Summary: This observational study involving patients with acute brain injury undergoing treatment with an external ventricular drain consists of three subprojects, aiming to:
1. investigate various biomarkers, with a primary focus on the development of cerebrospinal fluid lactate in relation to ventriculostomy-associated infection;
2. compare proximal and distal sample results obtained from an external ventricular drain;
3. describe the natural progression of various biomarkers in blood and cerebrospinal fluid following acute ...