U.S., Dec. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07260825) titled 'Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial' on Nov. 21.
Brief Summary: We are looking to see if patients using both topical testosterone and estrogen will have a greater improvement in pain with vaginal penetration compared to those using topical estrogen alone.
Study Start Date: Dec., 2025
Study Type: INTERVENTIONAL
Condition:
Vulvodynia
Dyspareunia
Lichen Sclerosus of Vulva
Intervention:
DRUG: Estradiol 0.01% Vag Cream
0.01% Estradiol cream, 1g to be applied to the vestibule twice daily for 12 weeks
DRUG: testosterone 0.1% and estradiol 0.01% vaginal cream
0.01% ...