U.S., Dec. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07294612) titled 'Use of Platelet-Rich Fibrin in Bladder Exstrophy Repair' on Dec. 08.
Brief Summary: Bladder exstrophy-epispadias complex (BEEC) is a rare condition in which the bladder and surrounding structures do not form normally. Surgery is required to close the bladder and restore normal anatomy, but complications such as penopubic fistula and wound breakdown are common after repair. Platelet-rich fibrin (PRF) is a material obtained from a patient's own blood that contains healing factors and may improve wound healing.
This prospective randomized controlled study evaluates whether applying autologous PRF during primary bladder exstrophy repai...