U.S., Sept. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07151417) titled 'Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.' on Aug. 13.
Brief Summary: The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving recovery in adults undergoing surgery for severe knee arthritis or injury.
The main questions it aims to answer are:
Does adding a steroid to the injection improve pain control and reduce opioid use after surgery? Is the newer extended-release steroid (Zilretta) more effective and safer-especia...