U.S., July 9 -- ClinicalTrials.gov registry received information related to the study (NCT07054489) titled 'UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF' on March 24.
Brief Summary: This study will use polygenic scores, a tool which describes differences in genetics, to examine effectiveness of beta blocker medication in heart failure patients with ejection fraction of 41-50 percent. The study will also assess beta blockers' effect on the changes in left ventricular end-systolic volume index by MRI.
Study Start Date: July 28
Study Type: INTERVENTIONAL
Condition:
Heart Failure
Polygenic Score
Intervention:
OTHER: Beta blocker
Participants randomized to intervention will be dosed and titrated on beta...