U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT06891300) titled 'Understanding and Treating Suicidal Ideation with Ketamine' on March 12.

Brief Summary: The goal of this clinical trial is to treat active suicidal ideation in individuals with Major Depressive Disorder (MDD) using ketamine and to understand suicidal ideation by examining biological mechanisms using magnetic resonance imaging (MRI), and psychological mechanisms through validated clinical scales and qualitative interviews. The main questions it aims to answer are:

1. Will ketamine will reduce suicidal ideation in a significant proportion of study participants?

2. Will reduction in suicidal ideation will be accompanied by rapid cha...