U.S., Oct. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07204093) titled 'Ultra-Safe Hormonal Strategy: Transdermal Estradiol Added to Progestins for Endometriosis' on Sept. 08.
Brief Summary: Endometriosis is a chronic, estrogen-dependent disease affecting women of reproductive age, associated with pelvic pain, infertility, and reduced quality of life. Progestins are the standard first-line therapy, but long-term treatment requires well-tolerated regimens that balance efficacy with patient satisfaction.
This study will compare two combinations of progestins with natural transdermal estradiol-dienogest versus drospirenone-to evaluate which regimen provides greater patient satisfaction after 6 months of th...