Clinical Trial: TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

U.S., Nov. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07223203) titled 'TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy' on Oct. 29.

Brief Summary: The purpose of this study is to:

* Determine the efficacy of nucresiran in patients with hATTR-PN by evaluating the effect on neurologic impairment, quality of life, nutritional status, disability, and gait speed

* Demonstrate superiority of nucresiran compared to in-study vutrisiran with respect to serum transthyretin (TTR) levels

Study Start Date: Dec. 31

Study Type: INTERVENTIONAL

Condition: Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy...