Clinical Trial: Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

U.S., Nov. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07225348) titled 'Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device' on Nov. 03.

Brief Summary: The first goal of this clinical trial is to learn if topical application of PLLA in conjunction with a microneedling treatment works to treat perioral wrinkles in adults. The second goal is to see whether the application of topical PLLA is more effective before or after a microneedling treatment. The main questions it aims to answer are:

* Is PLLA present within the MN channels from in vivo biopsy samples?

* Is it safe to combine topical PLLA and MN in the treatment of perioral wrinkles, as determined by the incidenc...