U.S., April 3 -- ClinicalTrials.gov registry received information related to the study (NCT06907212) titled 'Transcriptional Changes in Isolated Human Adipocytes During Obesity' on Dec. 16, 2024.
Brief Summary: Adipocytes play an important role in our body through their function as metabolic energy stores in the form of fat deposits, which are stored when metabolic energy is in excess and released when energy levels are low. In severe obesity, adipose tissue grows through the production of more adipocytes from stem cells (hyperplasia) and the increase in the size of existing adipocytes (hypertrophy). This ability of adipocytes, to maintain their functionality during tissue expansion, is critical in determining the development of obesity-re...