Clinical Trial: Towards a More Standardized Bicuspid Aortic Valve Repair: Rationale and Design of CONTOUR Trial

U.S., March 12 -- ClinicalTrials.gov registry received information related to the study (NCT06869954) titled 'Towards a More Standardized Bicuspid Aortic Valve Repair: Rationale and Design of CONTOUR Trial' on Jan. 22.

Brief Summary: Background: Between one-third and one-half of patients with bicuspid aortic valve (BAV) disease develop significant aortic regurgitation (AR) at a young age, leading to cardiomyopathy and heart failure. Aortic valve repair is an evolving and still underused strategy in BAV patients with AR. The lack of sufficient standardization remains the main limitation of current repair techniques, resulting in an increased risk of AR recurrence and reoperation. The most controversial issue is the stabilization of the BAV ...