U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT06942390) titled 'Topical Metformin Versus Topical Ketotifen in Melasma Treatment' on March 26.
Brief Summary: The study aims to evaluate and compare the efficacy and safety of a new formulation of topical metformin (nanoparticles) versus topical ketotifen (nanoparticles), both alone and combined with micro-needling, for the treatment of melasma. It is a double-blinded, randomized, split-face controlled clinical study involving 102 female patients diagnosed with bilateral melasma.
Study Start Date: June 01
Study Type: INTERVENTIONAL
Condition:
Melasma
Intervention:
DEVICE: Micro-Needling Combined with ketofin and metformin
After micro-needlin...