U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07423247) titled 'Tirzepatide (Spartina) in Obese Kidney Transplant Recipients' on Feb. 08.
Brief Summary: Post-transplant obesity is a common complication after kidney transplantation, largely attributed to recovery from uremia, increased appetite, sedentary lifestyle, and long-term corticosteroid exposure. Obesity in kidney transplant recipients increases the risk of cardiovascular disease, post-transplant diabetes mellitus (PTDM), and may contribute to graft injury through hyperfiltration-related mechanisms, potentially leading to reduced graft survival. Current approaches for weight management in transplant recipients, including lifestyle modific...