U.S., Feb. 14 -- ClinicalTrials.gov registry received information related to the study (NCT06825143) titled 'Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury' on Jan. 21.
Brief Summary: The objective of this clinical trial is to better understand how lactate, a naturally occurring energy substance, can be used to lessen damage to the vascular system in adults with a high cardiovascular disease risk.
The main questions it aims to answer are:
1. Does giving lactate intravenously reduce injury to the vascular system?
2. Does giving lactate intravenously together with blood flow occlusion - known as ischemic preconditioning, reduce vascular injury better than blood flow occlusion by itself?
3. How does lactate help ...