U.S., Nov. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07240350) titled 'The Role and Regulatory Mechanism of Germinal Center Immune Response in Hepatitis B Virus Infection' on June 19.
Brief Summary: The purpose of this observational study is to investigate the structure and composition of germinal centers in individuals with chronic HBV infection. The primary questions it aims to address are:
What are the phenotypes, functions, and complexity of B cell clones of the immune cells within the germinal centers of chronic HBV-infected individuals? Do chronic HBV-infected individuals have ectopic germinal centers in the liver? This will be studied by collecting peripheral blood and discarded liver, lymph no...