U.S., Jan. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07358754) titled 'The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor' on Jan. 13.
Brief Summary: Fibromyalgia is a chronic pain syndrome characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive symptoms. Central sensitization is considered a key mechanism in the pathophysiology of fibromyalgia; however, the underlying biological markers have not been fully clarified.
Brain-derived neurotrophic factor (BDNF) and S100B protein have been suggested to play roles in neuroinflammation and central pain processing. This observational, cross-sectional study aims to evaluate serum S100B and BDNF leve...