U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT06891508) titled 'The Placental Secretome as a Therapeutic Tool to Prevent Inflammation-induced Preterm Birth' on March 11.
Brief Summary: Preterm birth complicates 10% of all pregnancies and is the leading cause of perinatal morbidity and mortality worldwide. Intra-amniotic inflammation (IAI) and chorioamnionitis are well-established causes of PTB; however, a treatable infectious trigger is identified in only 50% of cases.In sterile IAI and/or preterm premature rupture of membranes (pPROM), there are currently no effective therapeutic options to reduce inflammation, promote amniotic sac healing, and prevent preterm birth. Growing evidence suggests ...