U.S., July 31 -- ClinicalTrials.gov registry received information related to the study (NCT07092475) titled 'The Impact of Intraoperative Methadone on Postoperative Opioid Use' on July 21.

Brief Summary: This is a single-institution, randomized controlled trial to assess the effectiveness of intraoperative methadone on postoperative opioid use, pain control, and recovery in patients undergoing autologous breast reconstruction. Findings from this trial would inform subsequent perioperative pain protocols and allow the possible integration of intraoperative methadone into multimodal analgesia protocols.

Study Start Date: Aug., 2025

Study Type: INTERVENTIONAL

Condition: Breast Cancer Opioid Use

Intervention: DRUG: Methadon

A long-actin...