U.S., April 23 -- ClinicalTrials.gov registry received information related to the study (NCT06939257) titled 'The Impact of Gender Affirming Hormone Therapy on Pain In Gender Minority Adults' on April 04.
Brief Summary: TRANSPIRE is an observational study of ~200 individuals who (1) will be initiating gender-affirming hormone therapy (GHT) or (2) are gender minority individuals who do not use GHT. The primary outcome will be to identify how the presence of chronic pain changes overtime with GHT through the use of surveys, quantitative sensory testing (QST), brain MRIs, and qualitative interviews.
Following recruitment and consent, participants will complete baseline survey measures and will repeat those measures at 1 months, 3 month, 6 mo...