U.S., Dec. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07309523) titled 'The Force Frequency Relationship in Heart Failure and Diabetes Mellitus: a Metabolic Aetiology?' on Dec. 15.
Brief Summary: The present investigation is a non-randomised, observational study involving an unselected but highly phenotyped cohort of patients undergoing pacemaker or defibrillator implantation from whom a small sample of fat and muscle will be taken from the operation site, and, in a subgroup, from the thigh muscle. A sample of blood wil also be taken from the vein of the heart, a peripheral vein and the artery at the wrist during the procedure at different heart rates and pacing modes, to describe how heart rate and hea...