U.S., April 17 -- ClinicalTrials.gov registry received information related to the study (NCT06930495) titled 'The Effect of Adiposity on Muscle and Microvascular Function in HFpEF' on March 31.
Brief Summary: This project is an observational study in patients with heart failure with preserved ejection fraction (HFpEF) who are candidates for treatment with weight loss medication to manage obesity or diabetes as part of their standard clinical care. This study will include multiple experimental visits before and after treatment (minimum 7 percent weight loss, between 9-12 months) to understand how increased adiposity and inflammation effects skeletal muscle and cardiovascular health and function and to examine the effect of medically directe...