U.S., July 31 -- ClinicalTrials.gov registry received information related to the study (NCT07092709) titled 'Tenecteplase for Intravenous Stroke Thrombolysis in Recent DOAC Users' on July 22.
Brief Summary: An investigator-initiated, multicenter, randomized, placebo-controlled, double-blind trial to determine the efficacy and safety of intravenous tenecteplase thrombolysis in acute ischemic stroke (AIS) patients with recent direct oral anticoagulants (DOACs) intake in improving the 90-day functional outcome.
Study Start Date: Aug. 01
Study Type: INTERVENTIONAL
Condition:
Acute Ischemic Stroke
Intervention:
DRUG: Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
Tenecteplase is administered as a single intravenous bolus at a dose o...