U.S., Sept. 17 -- ClinicalTrials.gov registry received information related to the study (NCT07176546) titled 'TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With Polyangiitis' on Aug. 18.
Brief Summary: This is a single center double-blind placebo-controlled study. Patients with GPA and active ears, nose, and throat (ENT) disease in at least two ENT domains, as defined after endoscopic visualization of the upper airway and audiometric evaluation, if applicable, by a single otolaryngologist using a validated GPA ENT disease activity score, will be eligible for inclusion. Patients will be treated with standard of care (SOC) treatment as determined by their treating rheumatologist. In addition to SOC, patients will be randomized...