U.S., May 9 -- ClinicalTrials.gov registry received information related to the study (NCT06962007) titled 'Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal' on April 27.
Brief Summary: Study Objective:
This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
Study Design:
This prospective, randomized, double-blind, controlled clinical trial enrolls adult patients (ASA physical status I-II, aged 18-70 years) undergoing elective surgery under general anesthesia with rocuronium. Patients will be randomized into four groups to receive either sugammadex at doses of 1 mg/kg, 2 mg/kg, or 4 mg/kg, or a c...