Clinical Trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ZX-8177 Tablets in Chinese Patients With Advanced Solid Tumors

U.S., Dec. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07310134) titled 'Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ZX-8177 Tablets in Chinese Patients With Advanced Solid Tumors' on Dec. 02.

Brief Summary: This study is an open-label, multicenter, phase I clinical trial involving dose escalation and dose expansion of ZX-8177 in patients with advanced unresectable, recurrent, or metastatic solid tumors.

The study consists of two stages: dose escalation and dose expansion. It primarily aims to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), biomarkers, and preliminary efficacy of ZX-8177 as a monotherapy with continuous admi...