U.S., June 14 -- ClinicalTrials.gov registry received information related to the study (NCT07019155) titled 'Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants' on June 12.

Brief Summary: Background:

Hereditary hematopoietic malignancy (HHM) syndromes are a group of inherited disorders that raises the risk of blood cancers. Many people with HHMs have changes in a gene (DDX41) that makes it more likely that they will develop myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), or other cancers. This natural history study will explore the link between HHM syndromes and these diseases.

Objective:

To study the link between HHM and MDS/AML.

Eligibility:

People aged 1 month and old...