U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT06880094) titled 'Study of Congenital Orofacial Clefts by Implementing Optical Genome Mapping' on March 11.
Brief Summary: Orofacial clefts, the most common congenital craniofacial malformations, have a complex etiology involving an interaction between genetic and environmental factors.
Chromosomal abnormalities, including structural variations, represent a major cause of human pathology. Recently, technological developments and the introduction of next-generation sequencing (NGS) technologies have revolutionized the field of medical genetics.
Optical genome mapping (OGM) is an innovative, high-resolution "long read" technique that enables the ide...