U.S., June 11 -- ClinicalTrials.gov registry received information related to the study (NCT07012109) titled 'Study of BEBT-507 Injection in Subjects With Polycythemia Vera (PV)' on May 29.
Brief Summary: This is a multicenter, open-label Phase I clinical trial of BEBT-507 in subjects with polycythemia vera(PV). Phase Ia is a single-agent dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), preliminary efficacy, and pharmacodynamics of BEBT-507 in subjects with PV . Based on the results of Phase Ia, two doses will be selected for further evaluation in Phase Ib to assess the efficacy, safety, and PK profile of BEBT-507 in subjects with PV , and to recommend a dose for Phase III clinical trials.
Study S...