Clinical Trial: Study Comparing Safety and Immunogenicity of Intranasal COVID-19 Vaccine and MRNA Booster in Healthy Adults

U.S., Feb. 12 -- ClinicalTrials.gov registry received information related to the study (NCT06821126) titled 'Study Comparing Safety and Immunogenicity of Intranasal COVID-19 Vaccine and MRNA Booster in Healthy Adults' on Jan. 28.

Brief Summary: This Phase I/II trial in France evaluates safety and immunogenicity of a booster dose of an intranasal COVID-19 vaccine (LVT-001) versus a booster dose of a COVID-19 mRNA vaccine (Pfizer-BioNTech) in healthy adult volunteers.

As a first-in-human trial, Phase I will assess the safety and immunogenicity of three escalating doses of the LVT-001 vaccine across 3 cohorts of 12 volunteers per dose level.

Based on cumulative data collected up to Day 28 visit from the last included participant in the Phas...