Clinical Trial: Study Assessing Pain Relief After Replacement of the Knee

U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT06799845) titled 'Study Assessing Pain Relief After Replacement of the Knee' on Jan. 24.

Brief Summary: The goal of the ATX101-TKA-004 clinical trial aims to evaluate the efficacy and safety of ATX101 1,500 mg in participants undergoing primary unilateral total knee arthroplasty. The study will compare the effectiveness of ATX101 with a saline placebo and bupivacaine, an active comparator. Additionally, it will assess opioid consumption among participants receiving ATX101 versus those given the saline placebo and bupivacaine. The trial will also focus on the safety and tolerability of ATX101 in the participants.

Study Start Date: Feb., 2025

Study T...