Clinical Trial: Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure

U.S., Feb. 19 -- ClinicalTrials.gov registry received information related to the study (NCT06831825) titled 'Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure' on Jan. 23.

Brief Summary: This clinical trial investigates the safety and preliminary effectiveness of YAP101, a gene therapy designed to improve heart function in adults with ischemic heart failure and reduced ejection fraction (HFrEF). Ischemic heart failure, often resulting from a prior heart attack, leads to poor heart function and quality of life. Current treatments are limited, and there is an urgent need for new therapies.

YAP101 works by delivering a gene therapy using a specialized vector to heart cells, ta...