U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT06798844) titled 'Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease' on Jan. 20.
Brief Summary: Freezing of gait (FOG) is a severely disabling gait disorder in Parkinson's disease (PD). Its poor response to current therapies reflects the shortfall in current knowledge on its exact pathophysiology. Case series suggest a therapeutic promise of spinal cord stimulation (SCS) for FOG, but double-blind randomised controlled trials with reliable FOG assessments are lacking.
This randomised, double-blind, placebo-controlled cross-over trial aims to define the outcome, safety, optimal stimulation paradigm and underlying mechanism of SCS for...