U.S., Dec. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07274475) titled 'Smoking Harm Reduction Using E-cigarettes and Cytisine' on May 29.
Brief Summary: Smoking remains the leading cause of preventable death globally, with high prevalence in disadvantaged populations despite access to free nicotine replacement therapy (NRT) and counseling through Ontario's STOP Program. This study aims to evaluate the acceptability, feasibility, and comparative effectiveness of e-cigarettes and cytisine as harm-reduction tools for individuals who continue to smoke despite standard treatments. Over four years, 6,000 STOP participants who smoke >=5 cigarettes daily at six months post-treatment will be randomized to recei...