Clinical Trial: Sivelestat Treatment for Postoperative Organ Protection in Type A Aortic Dissection

U.S., Sept. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07156656) titled 'Sivelestat Treatment for Postoperative Organ Protection in Type A Aortic Dissection' on Aug. 20.

Brief Summary: The goal of this multicenter, double-blind, randomized controlled trial is to learn if sivelestat sodium (Siv) can protect the organ function in patients suffered operation for acute type A aortic dissection. The main questions it aims to answer are:

* Can the 3-day-treatment of Siv enlarge the Day-0-to-Day-5 drop in the organ-health score (SOFA score)?

* Can this treatment significantly shrink the area under the SOFA curve from first dose to Day 5?

* Can this treatment significantly improve the end of patients in 28 da...